Discover the top places to see when driving from Auburn, Nebraska to Knoxville, Tennessee. Explore the Ozark Mountains, St. Louis and Nashville, and the Great Smoky Mountains.

Planning a road trip from Auburn, Nebraska to Knoxville, Tennessee? Check out our breakdown of the different routes, distance, time, tolls, and gas prices to help you choose the best option for your budget.

Planning a road trip from Auburn, Nebraska to Knoxville, Tennessee? Check out our ultimate guide to the fastest and most scenic routes, complete with estimated driving times based on traffic patterns.