Discover the best of the southeast with our list of top places to see on your road trip from Ashland, Ohio to North Myrtle Beach, South Carolina. From the Great Smoky Mountains to lively Myrtle Beach and the vibrant cities of Charleston, Asheville, and Raleigh, this road trip has it all.

Planning a road trip from Ashland, Ohio to North Myrtle Beach, South Carolina? Check out this post for estimates of gas and toll costs on popular routes.

Planning a road trip from Ashland, Ohio to North Myrtle Beach, South Carolina? Find out the fastest and slowest routes and estimated driving times in this guide.