Embark on an adventure through picturesque towns, national parks, and scenic vistas when driving from Asheville, North Carolina, to Islesboro, Maine. Check out our top places to see along the way, featuring Shenandoah and Acadia National Parks, New York City, Mystic Seaport Museum, and Portland.

Wondering about the cost of driving from Asheville, NC to Islesboro, Maine? Explore our guide to different routes, estimated distance & cost, travel time, gas prices, and toll roads. Happy driving!

Planning a road trip from Asheville, North Carolina to Islesboro, Maine? Read our blog to discover the fastest and slowest routes, distance, and estimated travel time based on traffic patterns.