Discover the top destinations for an unforgettable road trip from Arkansas to South Carolina. Experience Southern cuisine, national parks, and beaches along the Great River Road and more.

Plan your next road trip to South Carolina! Check out the cost of driving from Arkansas to South Carolina based on current gas prices and toll fees.

Planning a road-trip from Arkansas to South Carolina? Read on to discover the fastest and slowest routes, the distance, and estimated travel times based on traffic patterns.