Discover the top five best places to visit on a trip between Appleton, Wisconsin and Stafford, Connecticut. From the natural wonder of Niagara Falls to the bustling city life of Chicago, there's something for everyone.

Planning a road trip from Appleton, Wisconsin to Stafford, Connecticut? Check out our breakdown of the cost of driving via different routes based on gas prices and toll fees.

Looking to drive from Appleton, Wisconsin to Stafford, Connecticut? Read on for tips on the fastest and slowest routes, traffic patterns, and estimated driving times.