Embark on an adventure and discover fun attractions and unique sights while driving from Appleton, Wisconsin to Murphy, North Carolina. Check out our list of top places to visit and plan your trip today!

Discover the cost of driving from Appleton, WI to Murphy, NC. We break down the distance, cost, and time for the top three routes. Plan your road trip today!

Plan a road trip from Appleton, WI to Murphy, NC with ease. Discover several route options, travel time, and best time to beat traffic. Enjoy scenic stops on the way.