Embark on an unforgettable road trip from Appleton, Wisconsin to Charleston, South Carolina! Discover the top places to see along the way with our friendly guide.

Planning a road trip from Appleton, Wisconsin to Charleston, South Carolina? We break down the cost of different routes, distance, and time to complete each.

Planning to road trip from Appleton, Wisconsin to Charleston, South Carolina? Learn about the fastest and slowest routes, the distance, and traffic patterns in this guide.