Discover the top five must-visit destinations on a road trip from Ann Arbor, Michigan, to Knoxville, Tennessee. Explore horse farms, natural wonders, theme parks and more!

Planning a road trip from Ann Arbor, Michigan, to Knoxville, Tennessee? Check out this guide with estimated fuel costs, travel time, and toll prices for different routes to help you plan and budget your trip.

Planning a road trip from Ann Arbor, Michigan to Knoxville, Tennessee? Check out our guide for the fastest and slowest routes, distance, and driving times based on traffic patterns.