Discover five unexpected places to stop on a road trip from Ankeny, Iowa to University City, Missouri. From hiking at Tallgrass Prairie Preserve to wine tasting in Hermann, there's something for everyone on this adventure.

Planning a trip from Ankeny, Iowa to University City, Missouri? Read this article to discover the different possible routes, their costs, and the best recommendations based on current gas prices.

Plan your road trip from Ankeny, Iowa to University City, Missouri with our guide. We explore the different route options, the fastest and slowest routes, and estimated drive times.