Take a road trip from Anderson, South Carolina, to Kissimmee, Florida to explore breathtaking locations. Check out our list of top places to visit along the way.

Planning a road trip from Anderson, SC to Kissimmee, FL? Check out our breakdown of gas and toll expenses for the three available routes based on current gas prices.

"Plan your road trip to Kissimmee, Florida from Anderson, South Carolina. Learn about the fastest, slowest, and scenic routes, distance, and travel time under peak and low-traffic conditions."