Discover the top places to explore when driving from Ames, Iowa to Salem, West Virginia. From national parks to small historic towns, this road trip is full of adventure.

Planning a road trip from Ames to Salem? Check out our guide to the cost of different routes based on current gas prices. Explore your options and plan ahead!

Looking to plan a road trip from Ames, Iowa to Salem, West Virginia but don't know how long it will take? Check out our guide featuring different routes, traffic patterns, and estimated driving times.