Discover the top destinations to explore on your road trip from Alton, Illinois to Lake Saint Louis, Missouri. Read on for a list of must-visit places, from museums to botanical gardens and historic sites.

Planning a trip from Alton, Illinois to Lake Saint Louis, Missouri? Check out our breakdown of three different routes to find the most affordable option based on current gas prices and tolls.

Discover the best routes and estimated driving times from Alton, Illinois, to Lake Saint Louis, Missouri, and enjoy your road trip to the fullest.