Discover the top places to see on a road trip from Alexandria, Louisiana to City of Syracuse, New York. From Missouri's Gateway Arch to Niagara Falls, enjoy the beauty and culture of America's heartland.

Planning a road trip from Alexandria, Louisiana to Syracuse, New York? Check out our breakdown of routes, distances, times, and costs, including gas prices and tolls, to help you budget accordingly.

Looking to drive from Alexandria, Louisiana, to Syracuse, New York? Read about the fastest and slowest routes, distance, and time taken, including traffic patterns and tips for a long drive.