Explore the top places to see when driving from Affton to St. Louis, Missouri, including Forest Park, the Gateway Arch, City Museum, Anheuser-Busch Brewery, and Missouri Botanical Garden.

Plan your trip from Affton, Missouri to St. Louis, Missouri with ease. This guide provides the cost of gas and tolls for 4 different routes based on current gas prices. Safe travels!

Discover the time it takes to drive from Affton, MO to St. Louis, MO. Learn about the fastest and slowest routes and the distance, and time it takes based on traffic patterns.